The Role of M1 in Neuromodulation for Pain

Chronic pain remains a major clinical challenge worldwide, increasing interest in evidence-based neuromodulation approaches that target the brain’s pain-processing networks. Recent European and international guidelines on repetitive transcranial magnetic stimulation (rTMS) highlight the primary motor cortex (M1) as a key target for pain modulation, with strong evidence supporting its use in neuropathic pain and growing evidence in conditions such as fibromyalgia.

In this educational webinar Daniel Ciampi de Andrade, MD, PhD — neurologist, professor at Aalborg University, and researcher affiliated with the Center for Neuroplasticity and Pain — will explore the evolving role of M1 in chronic pain management and the latest clinical guidance surrounding rTMS for pain.

Professor Daniel Ciampi de Andrade, MD, PhD.

Dr. Ciampi is a neurologist, professor at the Center for Neuroplasticity and Pain at Aalborg University’s Faculty of Medicine in Denmark. His research focuses on symptom control in neurological diseases, particularly pain. He has a special interest in the use of non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) to investigate and modulate pain-related neural circuits. He serves as Vice President for Research at EFIC (European Pain Federation) and is a Section Editor for the European Journal of Pain. He has authored more than 200 peer-reviewed publications and has been awarded European research grants for his work on pain mechanisms.

Supporting studies:

Pharmacotherapy and non-invasive neuromodulation for neuropathic pain: a systematic review and meta-analysis

Beyond trial-and-error: Individualizing therapeutic transcranial neuromodulation for chronic pain

Differential Effects of Repetitive Transcranial Magnetic Stimulation on Mood and Pain Symptoms in People With Chronic Pain and Major Depressive Disorders-A Review

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